Liquid Handling: Microplate Washers and Dispensers > Microplate Washers
The gold standard of microplate washers
Cell-friendly design for high quality results
Automate magnetic and filtration bead-based assays
Self-maintaining design with patented ultrasonic bath
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Manifold tube clogs are the most common source of failure on plate washers. The built-in Ultrasonic Advantage allows the instrument to clean buildup in the manifold tube automatically, without removing it from the instrument. |
Hands-off self-testing Verify™ Technology Option
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The Verify Technology option eliminates tedious manual procedures by using an ultrasonic probe (1) to check dispense and aspirate performance. Test results are automatically displayed (2) and indicate tubes that may require additional cleaning. |
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384-well
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96-well
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Optimized Cell Washing
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4-Buffer Switching
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Biomagnetic Separation**
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Vacuum Filtration**
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405TSHT
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405TSHTV
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405TSU
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405TSUV
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405TSUS
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405TSUSQ
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405TSUVS
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405TSUVSQ
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405TSR
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405TSRV
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405TSRS
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405TSRSQ
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405TSRVS
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* 96-well washing available with optional manifold PN 1170010, sold separately
** With available accessory module sold separately
| 405™ TS Microplate Washer Configurations | ||
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| Feature | Design | |
| HT | Faster 384-well microplate washing |
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| V | Automated Internal 4-Buffer Switching | |
| S | Ultrasonic Advantage™ |
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| U | 96-/384-well microplate washing |
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| R | 96-well microplate washing |
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| Q | Verify™ technology |
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| General | |
| Microplate types | 96- and 384-well Low profile and standard height Solid and filter bottom (option) |
| Onboard software | Create, edit or run multiple protocols |
| Software (computer control) | LHC2 pc software (option) LHC2 Secure for 21 CFR Part 11 compliance (option) SiLA Compliant driver (option) |
| Separation | Biomagnetic separation, vacuum filtration (optional) |
| Shaking | Programmable up to 60 minutes Slow, medium, fast or variable |
| Soaking | Programmable up to 60 minutes |
| Ultrasonic Advantage™ | Yes (option) |
| Verify™ clog detection | Yes (option) |
| Automation | BioStack and 3rd party automation compatible BioSpa 8 Automated Incubator compatible |
| Washing | |
| Manifold types | 96-well washing: 96-tube manifold - straight dispense tubes 96- and 384-well washing: 96-tube Dual-Action manifold - 20° angled dispense tubes 384-well washing (fast): 192-tube Dual-Action manifold - 7° angled dispense tubes |
| Volume range | 25-3,000 µL/well (192-pin manifold) 50-3,000 µL/well (96-pin manifold) |
| Wash cycles | 1 - 250 |
| Buffer/reagent selection | Auto switching (internal) for up to 4 buffers (option) |
| Supply bottle | 4 L or 10 L (optional) |
| Dispense precision | <3% CV: 300 µL/well (96-well washing) <4% CV: 80 µL/well (384-well washing) |
| Residual volume | < 2 µL/well (96- & 384-well plates) 96-tube manifold for 96 wells; 192-tube for 384 wells |
| Wash speed | 96-wells, 300 µL/well, 3 cycles; <30 seconds 384-wells,100 µL/well, 3 cycles: <80 seconds 384-wells, 400 µL/well, 1 cycle: <20 seconds |
| Flow rates | High flow to low flow Optimized rates for cell assays |
| Sterilization | Chemical |
| Vacuum filtration | Selectable: Approximate final at 30 seconds: Lowest: -38 mmHg Low: -113 mmHg Medium: -200 mmHg High: -390 mmHg Highest: -506 mmHg Vacuum filtration time range: 5 to 999 seconds |
| Physical Characteristics | |
| Power | 100 - 240 Volts AC. 50/60 Hz |
| Dimensions | 14" W x 17" D x 10" H (35.6 x 43.2 x 25.4 cm) |
| Weight | With internal buffer switching - 36 lbs (16.5 kg) Without - 30 lbs (13.5 kg) |
| Regulatory | |
| Regulatory | CE and TUV marked. ROHS compliant. In Vitro Diagnostic use models are available. |
A combination of angled dispense tubes and both highly adjustable dispense and aspiration rate settings make 405 TS the ideal washer for cell-based assays. The gentle flow rates and side-wall dispensing position ensure the integrity of cell monolayers. 
Multiplexed bead-based assays are very common, and 405 TS easily accommodates necessary wash steps. Magnet accessories for biomagnetic separation workflows, available in both flat and 4-zone ring designs, ensure high bead recovery (1). A vacuum filtration module is available for polystyrene bead assays (2).