405 TS Washer

Liquid Handling: Microplate Washers and Dispensers > Microplate Washers

405 TS Washer


The 405 TS Microplate Washer is #1 in life science research, known for its excellent performance and outstanding reliability.  The 405 TS has a unique set of features designed to efficiently, effectively wash cell-based assays, microsphere-based assays and ELISA, with outstanding results for every application.  The patented Verify™ technology automatically checks for manifold tube blockages before a wash cycle, and Ultrasonic Advantage™ automatically cleans any blocked manifold tubes. These functions save time and frustration, and ensure successful results.


Patented Verify™ clog detection technology and Ultrasonic Advantage™

Washer verifier

Verify™ technology, which runs an automated QC check for manifold tube blockage, and visually reports any failed wells. The patented Ultrasonic Advantage™ can then be used to automatically and thoroughly clean the aspirate and dispense manifolds.

High resolution, advanced touch screen user Interface


405 TS features high resolution touch screen user interface for intuitive and flexible programming of 96- and 384-well microplate wash protocols. The extensive onboard software seamlessly guides users through protocol development, instrument maintenance and operation.

405 TS

Programmable residual volume

405 TS

The 405 TS onboard software makes it simple to leave the wells empty or with the exact amount of residual your assay needs. Using the dimensions of the selected plate, the software automatically sets the aspiration height to leave the user-specified volume.

Password protection


Protocol critical protocols from unintended changes using the convenient password protection feature in the 405 TS software. Protected protocols can be viewed and run, but not modified by unauthorized users.

405 TS


USB flash drive ports for convenient file transfer and storage

405 TS thumb

Two USB ports on the 405 TS enable convenient file transfer, storage and operation.


Optimized for loosely adherent cell monolayers


The 405 TS can process sensitive cell-based assays with its angled dispense tubes and adjustable flow rates. The Dual-Action manifold and carrier offer X-Y-Z adjustment, perfect for optimizing plate positioning and residual removal for cell-based and other assays.

405 TS


Part #
Optimized Cell Washing
4-Buffer Switching
Biomagnetic Separation**
Vacuum Filtration**

* 96-well washing available with optional manifold PN 1170010, sold separately
** With available accessory module sold separately


405™ TS Microplate Washer Configurations
  Feature Design
HT Faster 384-well microplate washing
V Automated Internal 4-Buffer Switching  
S Ultrasonic Advantage™
  • Built-in ultrasonic cleaner for manifold self-maintenance
U 96-/384-well microplate washing
  • 96-tube (8 x 12) manifold
  • Dual-Action™
R 96-well microplate washing
  • 96-tube (8 x 12) manifold
Q Verify™ technology
  • Built-in clog detection for dispense and aspirate tubes


Microplate types 96- and 384-well
Low profile and standard height
Solid and filter bottom (option)
Onboard software Create, edit or run multiple protocols
Software (computer control) LHC2 pc software
LHC2 Secure for 21 CFR Part 11 compliance (option)
SiLA Compliant driver (option)
Separation Biomagnetic separation, vacuum filtration (optional)
Shaking Programmable up to 60 minutes
Slow, medium, fast or variable
Soaking Programmable up to 60 minutes
Ultrasonic Advantage™ Yes (option)
Verify™ clog detection Yes (option)
Automation BioStack and 3rd party automation compatible
BioSpa 8 Automated Incubator compatible
Manifold types 96-well washing: 96-tube manifold - straight dispense tubes
96- and 384-well washing: 96-tube Dual-Action manifold - 20° angled dispense tubes
384-well washing (fast): 192-tube Dual-Action manifold - 7° angled dispense tubes
Volume range 25 - 3,000 µL/well, in 1 µL increments
Wash cycles 1 - 250
Buffer/reagent selection Auto switching (internal) for up to 4 buffers (option)
Supply bottle 4 L or 10 L (optional)
Dispense precision <3% CV: 300 µL/well (96-well washing)
<4% CV: 80 µL/well (384-well washing)
Residual volume < 2 µL/well (96- & 384-well plates)
96-tube manifold for 96 wells; 192-tube for 384 wells
Wash speed 96-wells, 300 µL/well, 3 cycles; <30 seconds
384-wells,100 µL/well, 3 cycles: <80 seconds
384-wells, 400 µL/well, 1 cycle: <20 seconds
Flow rates High flow to low flow
Optimized rates for cell assays
Sterilization Chemical
Vacuum filtration Selectable: Approximate final at 30 seconds:
Lowest: -38 mmHg
Low: -113 mmHg
Medium: -200 mmHg
High: -390 mmHg
Highest: -506 mmHg

Vacuum filtration time range: 5 to 999 seconds
Physical Characteristics
Power 100 - 240 Volts AC. 50/60 Hz
Dimensions 14" W x 17" D x 10" H
(35.6 x 43.2 x 25.4 cm)
Weight With internal buffer switching - 36 lbs (16.5 kg)
Without - 30 lbs (13.5 kg)
Regulatory CE and TUV marked. ROHS compliant. In Vitro Diagnostic use models are available.