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The EL406 Combination Washer Dispenser offers fast, full plate washing along with three reagent dispensers in one, compact instrument. Its multiple capabilities include washing and dispensing for standard assays, plus biomagnetic separation and vacuum filtration protocols. The Dual-Action™ manifold optimizes washing for loosely adherent cell monolayers, while the patented Ultrasonic Advantage™ helps prevent blockages in the manifold tubes before washing, to reduce assay failure. Syringe pump and peristaltic pump dispensers each offer unique advantages, and the EL406 offers both, along with superior plate washing, on a single platform - making the EL406 a workhorse for your laboratory.



Applications for the EL406 Washer Dispenser run from simple dispense operations to full-scale automation of liquid handling steps in preparation for downstream processes. Here are a few important applications of the EL406.
  • Bulk reagent dispensing
  • Cell seeding

Melamine ELISA
Melamine ELISA: wash process by EL406

Post-EL406 media exchange validation
Post-EL406 media exchange validation, spheroids and cultured cells.

These are just a few examples of the many important applications for EL406. Visit our Applications page to see more.


BioTek Field Applications Scientists (FAS) and Product Specialists provide unparalleled scientific support, assisting with experimental planning and assay optimization on BioTek’s instrumentation and software. Learn how they can help move your science forward… faster!


Washing and multiple reagent dispensing


There’s no need for multiple instruments when you have an EL406 in the lab! The EL406 is microplate washer with peristaltic and syringe pump modules available to make it into an efficient multi-tasking system. For benchtop use or integrated into automated systems, the EL406 does the work of multiple instruments.

96-, 384- and 1536-well plate compatible


BioTek’s Dual-Action™ manifold quickly washes 96- and 384-well plates. For 1536 washing, unique aspirate and dispense manifolds rapidly dispense and aspirate across the plate. Wash speeds for the three plate types range from 13 seconds to 36 seconds, keeping all your processes efficient.



Gentle processing for cell-based assays


Cell-based assays can be challenging to wash - too often, cell monolayers are disrupted by vigorous dispensing or overly intense aspiration. The EL406 Dual-Action manifold and plate carrier have x-y-z adjustments, and flow rates are fully adjustable - to optimize parameters for even the most sensitive assays. Angled dispense tubes direct fluid flow to the well sides, further minimizing disruption.


Bead washing: magnetic and polystyrene


The EL406 is a powerhouse for many standard plate washing and dispensing protocols, but it also automates more complex operations like magnetic and polystyrene bead washing workflows – and it’s Luminex® xMap® approved. Bead washing is available for 96- and 384-well microplates.


Easy maintenance with Ultrasonic Advantage™


EL406 has a number of automated system maintenance features, including. BioTek’s Ultrasonic Advantage™. The dispense and aspirate tubes are immersed into the built-in ultrasonic bath in the priming trough while the automate cleaning program runs, dislodging and aspirating away salt crystal and protein buildup in the tubes.

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NIHTranslating Compounds into Therapies


Dr. Samuel Hasson is a post-doctoral fellow at the National Institutes of Health, National Center for Advancing Translational Sciences (NIH, NCATS), under the direction of Jim Inglese. The Inglese lab’s research goals include translating molecular or cellular phenotypes of human disease biology into innovative high-throughput screening (HTS) compatible drug discovery assays. Dr. Inglese’s team also seeks to develop new paradigms and technologies that advance chemical biology. Within the lab, Dr. Hasson is interested in the link between mitochondrial dysfunction and Parkinson’s disease, a chronic and progressive movement disorder, and works with cell-based and target-based assays. He created a set of high-content assays to report the modulation of mitochondrial quality control as it relates to the Parkinson’s disease pathology. These assays are being used to screen for genetic and small molecule effectors that control the cell’s ability to eliminate damaged mitochondria.




SILA Luminex xMAP Approval
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