product design

The BioTek BioSpa live cell analysis system offers unique benefits for a wide variety of live cell imaging applications in up to 8 microplates or other labware. With 5 imaging modes, the system enables a wide range of microscopy applications. Capture detailed cellular images, get cell-level analyses for migration and wound healing assays, 3D spheroid formation, and many other kinetic applications. Built-in scheduling, environmental monitoring, and available liquid handling for walk away automation. Multiple users can run simultaneous processes for maximum efficiency in the lab.

The BioSpa Live Cell Analysis System offers unique benefits for a wide variety of live cell imaging applications:

Fluorescent images of fibroblast


These are just a few examples of the many important applications for BioSpa Live Cell Analysis System. Visit our Applications page to see more.


BioTek Field Applications Scientists (FAS) and Product Specialists provide unparalleled scientific support, assisting with experimental planning and assay optimization on BioTek’s instrumentation and software. Learn how they can help move your science forward… faster!



   Five imaging modes

 Automated digital microscopy to 100x

The variety of imaging modes enable an astonishing range of microscopy applications, within a single, compact system. Automate workflows for up to 8 microplates or other labware, including cell culture dishes, and microscope slides.

   Broad magnification range


Capture the level of detail you need, from whole well montage to intracellular detail with 1.25x to 60x objectives available. The automated, 6-position turret makes it simple to capture multiple magnifications in a single workflow.

Four imaging modes, multiple imaging processes

   Environmental controls


Successful long term live cell assays rely on a controlled environment to keep cells healthy and aid proliferation. BioSpa has integrated temperature and CO2/O2 control and monitoring, plus humidity monitoring to protect cells during kinetic runs that last days or weeks.


   Automated objective turret


To efficiently view a variety of samples at a range of magnifications, install up to 6 objectives on the automated turret, and capture images automatically, within a single experiment.


   3D cell culture

3D cell culture

Gen5 software has powerful z-stacking capabilities to capture the important details of a 3D cell structure. Z-projection and image analysis provides in-depth information about the spheroid. Z-stacking montage capability brings powerful processing for 3D biologies.


   Patented laser autofocus


Provides increased reproducibility and speed, while decreasing phototoxic and photobleaching effect. Learn more about Laser Autofocus on the Technology Page.

Label-free cell counting

   Advanced cell-level analysis


Powerful tools like nuclear and cytoplasmic masking define critical, information-rich regions of interest for automated, detailed cellular analysis.


Compact and Efficient Design


The BioSpa Live Cell Analysis System easily fits inside commercially available containment enclosures and biosafety cabinets. The Baker Company offers a broad range of innovative solutions to provide isolation of cell lines and containment of potentially hazardous agents. Fluidics, power requirements, heat rejection, service and user interface ergonomics can all be accommodated.  BioTek and Baker continually work together to provide automated life science laboratories with the best possible solution. 

Compact and Efficient Design

Product Reviews

Customer Spotlight

Colorectal cancer cells Teasing Out Fine Details from the Tangled World of Chromosomes


Normal human cells contain 23 chromosome pairs, each encoding the genetic information of life as well as passing on inheritable traits from parents. Chromosomes are tightly folded into origami-like structures that are mind-boggling in their complexity, yet elegantly unfurled and refolded during cell division or mitosis. Tiny errors during mitosis can cause the formation of aneuploid cells containing an abnormal number of chromosomes and lead to miscarriage and health disorders such as Down syndrome. Additionally, these mistakes have been linked to tumorigenesis and accelerated tumor growth rates.



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