Lots of Stress, A Little Luck, and A Brand New Epoch!
Perhaps more than a typical researcher, Joël Tardivel-Lacombe’s research day is filled with stress. Mr. Tardivel-Lacombe’s team, Department 624, studies cellular response to stress using the pancreatic cell as a model at the Institut National de la Santé et de la Recherché Médicale (INSERM) in the heart of the Luminy Science and Technology park in Marseille, France. The lab’s goal is to understand the mechanisms of cancer metastasis and to find therapeutic targets that could be used as a therapy or cure for many cancer types. A total of six research teams study various molecular aspects of cellular stress including: biology of pancreatic stress, new cellular stress response pathways, therapeutic antibodies and immunotargeting (TAI), clinical and preclinical studies, regulation of signaling pathways and targeting stress proteins in prostate cancers.
Joël Tardivel-Lacombe and his team
Several readers were shared among the research teams: microplate readers were used for ELISAs in 96-well plates and MTT cell viability tests in 6- to 96-well plates; for UV quantification of DNA, RNA and proteins a cuvette spectrophotometer; and finally, a NanoDrop for micro-volume measurements.
Mr. Tardivel-Lacombe entered BioTek's, “Win a Free Epoch Spectrophotometer System” in 2009 on a whim. “I must admit that I never really imagined I could win the equipment being offered when I took part in the competition organized by BioTek,” he recollected.
The contest marked the launch of the Epoch™ Multi-Volume Spectrophotometer System. The system includes the monochromator-based Epoch Microplate Reader, for absorbance measurements from 200-999 nm in 6- to 384-well microplates and the Take3™ Multi-Volume Plate, used for measuring up to sixteen 2 µL samples, 1 cm cuvettes or BioTek's proprietary BioCell™ 1 cm quartz cuvette. Instrument control and data reduction are automatic with pre-programmed Gen5™ software.
Luck was on his side, because out of over 800 entries from 68 countries, the stress researcher was declared the winner! The new Epoch Spectrophotometer System was installed on February 25, 2010.
After several months of use, Mr. Tardivel-Lacombe reports that all of the research teams are using the user-friendly Epoch System, noting, “The new BioTek Epoch reader is a real plus for our team because it is highly polyvalent and lets us carry out our measurements in UV or visually in different volumes with one and the same device!”
To learn more about INSERM, visit their web site.