Customer Spotlights

Nothing can speak to the experience you'll encounter with BioTek like stories from our customers themselves. Customer satisfaction is our top priority. From Engineering to Manufacturing to Sales and Support, BioTek employees around the world are dedicated to providing the best product and best customer experience in the industry.

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Dr Francesco Paolo Fiorentino

How Leading Scientists in Italy are Performing State-of-the-Art Cell-Based Assays to Help Push Boundaries in Anticancer Drug Discovery
SelectScience Interview
23-May-17
Related Product: Cytation 5

Dr Francesco Paolo Fiorentino had long dreamed of starting his own company; two years ago, this dream became a reality when he and a colleague applied for and won funding to set up Kitos Biotech. Inspired by a talk from a researcher who had already made the leap from postdoc to entrepreneur, Francesco saw the opportunity to use his expertise in cell biology and preclinical research, whilst also embracing the technological shift from traditional manual methods to automation. Cell-based assay services at Kitos Biotech use the latest automated technologies to test anticancer compounds on a considerably larger scale than traditional manual methods, addressing the need for academic researchers, biotechs, and pharmaceuticals to access costly high-throughput technology.

In an interview with SelectScience®, Dr Fiorentino discussed the technology advancing cell-based assays for anticancer drug discovery and how he is improving services at Kitos Biotech.

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Dr. Eva Kuttner

Improving Joint Health with Putative Therapeutics at Matis, Iceland’s Food & Biotechnology Research Institute
SelectScience Interview
27-April-17
Related Product: Cytation 5

Matis is a leading food and biotechnology research institute in Iceland. Matis’ vision is to increase the value of food processing and food production, and to ensure the safety and quality of food and food products. SelectScience® spoke to Dr. Eva Kuttner, to learn more about the technology the company is using in its research.

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Cytation 5

Leveraging 3D Cancer Stem Cells to Conquer Cancer Relapse
10-April-17
Related Product: Cytation 5

In 2013, Dr. Angel Garcia Martin and Dr. Olatz Leis co-founded StemTek Therapeutics (Bilbao, Spain) as a biopharmaceutical company specializing in cancer stem cell research and drug discovery for novel anticancer therapies. Most chemotherapies and radiotherapies do not target these special cells, which may lead to post-therapy tumor relapse and expansion. Dr. Garcia Martin notes that although finding specific targets in cancer stem cells is complex, they are essential for a durable response in cancer treatment. StemTek eases some of this complexity for researchers by offering in vitro and in vivo screening methods and services based upon their patent-pending Cell2Sphere™ novel compound screening system.

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Dr. Gwendalyn Randolph

Seeing a Clear Slice of Life in Crohn’s Disease
3-April-17
Related Product: Cytation 5

Dr. Gwendalyn Randolph started her career studying immune cell trafficking in and out of tissues, particularly myeloid cells that initiate immune responses and those that derive from monocytes in the blood. In the chronic cardiovascular disease atherosclerosis, she wondered if there was an association between disease progression and the accumulation of myeloid cells because they couldn’t traffic out of the area. As part of this research, she looked at lymphatic vessels, as they drain fluid and traffic certain immune cells to lymph nodes.

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Universidad de La Frontera

Time to move forward with confidence in results
3-April-17
Related Product: Synergy HTX

Dr. Jorge Farías studies cellular and molecular mechanisms in fish spermatozoa as part of his role as the Director of Chemical Engineering at the Universidad de La Frontera in Temuco, Chile. Spermatogenesis, which is the development of sperm, is a delicate balance between cell proliferation, differentiation and apoptosis, and disruptions can have profound implications.

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Kirk McManus

Decreasing Cancer Morbidity Through Colorectal Cancer Research
23-December-16 video
Related Products: Cytation 5, EL406, BioSpa 8

Kirk McManus, Associate Professor, University of Manitoba, and Senior Scientist, CancerCare Manitoba, discusses his ground breaking colorectal cancer research, which aims to minimize the morbidity rates of cancers. Learn how this research is being carried out using an advanced instrument workflow from BioTek, which has streamlined his team's cancer cell studies to great effect. 

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 Dr. Johnson with Miranda Neubert

Dreaming Big When It Comes to the Possibilities
15-December-16
Related Products: Cytation 5

Metals play a very important role in biology, as metal ions are associated with an estimated 40% of all proteins. In bacteria, dedicated acquisition and efflux systems tightly control metal homeostasis. Some metals, such as iron, are so critical to bacterial physiology that in most cases only the acquisition system exists; while others, such as copper, are so toxic that only efflux systems exist. It is this copper toxicity that is of particular interest to Dr. Michael Johnson and his new laboratory in the Department of Immunobiology at the University of Arizona’s College of Medicine. Dr. Johnson notes that although bacteria can develop resistance, as seen against modern antibiotic therapies, they remain vulnerable to the toxic effects of copper. His research aims to unravel this age-old mystery by understanding how copper is toxic to bacteria, and how bacteria overcome copper toxicity.

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Southern Methodist University

Advancing Cancer Research Using High Throughput Screening in Cancer Cell Lines
SelectScience Editorial Article
14-December-16
Related Product: Cytation 5, Gen5, EL406

Amila Nanayakkara, a researcher in the laboratory of Dr Pia Vogel and Dr John Wise in the Department of Biology at the Southern Methodist University of Dallas, spoke to SelectScience® about the lab’s techniques and technologies and how they are used to advance their cancer research. 

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Dr. Steve Quiros

Striking a Lethal Blow to Chemoresistance
15-November-16
Related Product: Cytation 3

Malignant tumors are heterogeneous, demonstrating a diverse population of cell morphologies and phenotypic profiles. This results in specific cancer types expressing dissimilar characteristics from one patient to the next, and chemotherapies targeted towards a specific tumor may not eradicate the entire cellular mass. Dr. Steve Quiros and his colleague, Dr. Rodrigo Mora, at the Tumor Chemosensitivity Laboratory (LQT), Faculty of Microbiology at the University of Costa Rica are taking a close look at mechanisms to circumvent these hurdles and increase the effectiveness of chemotherapies, cancer diagnostic tools and personalized treatments.

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Dr. Katyal

New, Automated Path to Ask More Complicated Questions and Receive Enhanced Answers
27-September-16
Related Products: Cytation 5, Gen5, EL406

With more than a decade of experience, few researchers have more expertise than Dr. Sachin Katyal when it comes to the comet assay, also known as single cell gel electrophoresis (SCGE). As a post-doc at St. Jude Children’s Research Hospital, Dr. Katyal incorporated this assay to study neural damage, and now in his dual role as Assistant Professor in Pharmacology and Therapeutics at the University of Manitoba and Senior Scientist with the Research Institute in Oncology and Hematology (RIOH) at CancerCare Manitoba in Winnipeg, Canada, Dr. Katyal applies the comet assay in his studies on brain tumors and other cancers.

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Erik S.

A Simple Yet Powerful Method for Measuring Real-Time Kinase Activity
14-September-16
Related Products: Synergy Neo2, BioStack

AssayQuant Technologies, Inc., in Marlborough, Massachusetts is a growing Life Science company that develops innovative enzyme assay formats for a quantum improvement in performance and productivity to enable discovery or accelerate drug development. Its founders, Dr. Erik Schaefer and Dr. Barbara Imperiali, each impart a wealth of experience that allows AssayQuant to deliver exceptional value to their customers.

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The McManus Lab

Identification and Characterization of Cancer Risk Factors Using High Throughput Cell Screening
SelectScience Editorial Article
17-June-16
Related Product: Cytation 3EL406, BioSpa 8

Dr Kirk McManus, Associate Professor in the Department of Biochemistry & Medical Genetics at the University of Manitoba and a Senior Scientist within the Research Institute in Oncology at CancerCare Manitoba, spoke to SelectScience® about his cutting-edge cancer research, which aims to identify cancer causing genetic abnormalities and screen potential therapies.

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Quote

Bringing Lab Quality Biodetection Technology to the Field
SelectScience Editorial Article
20-April-16
Related Product: FLx800

SelectScience® spoke to Dr Gabriel Peckham, Principal Investigator, Black Ivory Biotech about his research into developing new transportable technologies for biodetection.

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Charles Teta

MultiFlo FX Wins Over Environmental Lab
14-December-15
Related Product: MutliFlo FX

In the Department of Environmental Science and Health at the National University of Science and Technology (NUST) in Bulawayo, Zimbabwe, Mr. Charles Teta specializes in ecotoxicology. His research includes uncovering the frequency and effects of endocrine disrupting chemicals in native fish, and analyzing hazardous chemicals such as heavy metals and pesticides in the environment that may have originated from municipal landfills, mines and urban effluents. With several kinetic and end-point assay techniques already employed, the manual processes were time consuming, and human error was an ever-present risk when dispensing into a microplate with a single-channel or multi-channel pipette. If reagents were added too slowly, or mixed incompletely, the assays had to be repeated, thereby doubling efforts, sample volume and costly materials.

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City of Hope

A Convenient Jump Start for Anti-tumor Immunity
7-December-15
Related Product: Cytation 3

In the Department of Immuno-Oncology in the Beckman Research Institute at City of Hope National Medical Center, Dr. Marcin Kortylewski and his group incorporate a “flank” strategy in the fight against cancer. Instead of directly focusing on tumor cells, which can evolve over time, the researchers target well-defined immune cell functions. Dr. Kortylewski explains that the immune cell protein, STAT3 (signal transducer and activator of transcription, third member of the family), plays the role of master regulator for normal immune response. STAT3 also performs a similar function when immune cells migrate into the tumor microenvironment. This creates an immunosuppressive effect that prevents a strong anti-tumor response, so blocking this protein can re-energize anti-tumor immunity. His research suggests that oligonucleotide-based therapeutics that inhibit STAT3 in a cell-selective manner may effectively restore the anti-tumor immune response.

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Likarda

More Effective Drug Screening with Cultured 3D Cell Clusters
20-November-15
Related Product: Cytation 5

Watch this video to learn more about the drug and product screening process at Likarda, a contract research organization. Dr Lisa Stehno-Bittel, President & CEO of Likarda, discusses the problems of screening drugs for efficacy. Due to the nature of cultured cells, it is very difficult to predict which drugs you’re working with are finally going to work in the human body. By employing the BioTek Cytation 5, Likarda is able to offer the most sophisticated 3D results, efficiently testing drugs in a representative manner.

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Swansea

Biocontrol of Invertebrate Pests Using Natural Agents: Investigating Host-Pathogen Interactions with the BioTek Synergy H1
24-June-15
Related Product: Synergy H1

Biocontrol agents provide a safer alternative to chemical pesticides and insecticides for the agricultural and forestry industries, as well as human health. In this video, Dr Bethany Greenfield, Post-Doctoral Research Assistant in the Biocontrol and Natural Products (BANP) Group at Swansea University, describes her research into the use of Metarhizium anisopliae for the control of mosquitoes. Hear how the BioTek Synergy H1 enables the group to efficiently perform a range of analyses, from protein quantification to measuring insect stress response.

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University of Manitoba

University of Manitoba
23-June-15
Related Product: Cytation 3

Like many researchers, Dr. Kirk McManus, Associate Professor in the Department of Biochemistry and Medical Genetics at the University of Manitoba, has many questions, and he and his team are very busy, looking for answers! The main goals of Dr. McManus' primary research area, colorectal cancer, are to a) identify aberrant genes that cause chromosome instability (CIN), and b) once these genes are found, identify new drug targets that exploit the aberrant genes through synthetic lethality.

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Fox Chase Cancer Center

2014 Cytation 3 Contest Winner
07-May-15
Related Product: Cytation 3

It's been a year since Dr. Jeffrey Peterson submitted the winning entry to BioTek’s "Think Possible" contest, earning his laboratory at Fox Chase Cancer Center a new Cytation 3 Cell Imaging Multi-Mode Reader. Here is an excerpt from Peterson's entry:

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Cytation 5

Investigating Novel Therapeutics for Cardiovascular Disease Using the BioTek Cytation 5 Cell Imaging Multi-Mode Reader
SelectScience Editorial Article
10-April-15
Related Product: Cytation 5

Discover how the Director of the Stanford Cardiovascular Institute uses this technology.

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Cytation 5

BioTek Supports A Better Way for Life Sciences Startups
05-December-14
Related Product: ELx405

Dr. Johannes Fruehauf is dedicated to helping life science and biotech startup companies transform novel scientific concepts into therapeutic products. When founding his first pharmaceutical venture several years ago, he remembers the huge cost and time investments needed to find space and build a laboratory. He says, “It wasn’t a good use of our resources. We would have realized greater value if the money and time had gone into our actual research efforts.”

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Cytation 5

Precision XS Helps to Create ‘Microplates’ from Paper
10-June-14
Related Product: Precision™ XS

Under the leadership of Dr. Ratmir Derda, researchers in the Derda Research Group at the University of Alberta Department of Chemistry and Alberta Glycomics Centre seek novel, portable platforms to aid in chemical, biological, clinical and even specialized 3D cell-based applications through microfluidics and micro-patterned paper. The far-ranging implications of this research are to increase consumable portability and affordability, and simplify processes, especially in developing nations or laboratories with limited resources. SyntArray, founded by Dr. Derda, governs commercialization of these unique microfluidic platforms.

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