Technical Resources
Technical resources are available to illustrate product specific capabilities and common applications for BioTek microplate instrumentation. These documents assist with both the operation of BioTek instrumentation to achieve peak performance, and their implementation in common experimental design.
Posters (148)
American Society for Cell Biology (1)
Biotherapeutics Analytical Summit (1)
Drug Discovery & Development (8)
- Automated Tissue Culture Cell Fixation and Staining in Microplates (08-May-13)
- Automation of a Luminescent Assay to measure UDP-glucuronosyltransferase (UGT) Enzyme Activity (11-Sep-09)
- A Simple and Robust Automated Kinase Profiling Platform using Luminescent ADP Accumulation Technology (13-Aug-09)
- Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds (13-Aug-09)
- The EL406™ Microplate Washer Dispenser Combines Thorough Washing and Precise Dispensing in One Space-Saving Instrument Configuration (01-Aug-08)
- Synergy™ 2 Multi-Mode Microplate Reader: A Novel Approach to Detection for HTS and Drug Discovery (19-Sep-06)
- Using BioTek’s ELx405™ Microplate Washer to Automate Washing of the QuantiGene® Reagent System (28-Jan-05)
- Fully Automated Sample Preparation and Nanoelectrospray MS Analysis Using ZipTips, the Precision 2000 and the NanoMate 100 (03-Sep-03)
ELRIG (7)
- Automation of a Generic Fluorescence Methyltransferase Activity Assay (15-Sep-11)
- Automation of a Novel Cell-Based ELISA for Cell Signaling Pathway Analysis (15-Sep-11)
- Automated Compound Profiling Applications for the Assessment of Lead Compound Off-target Effects (01-Jul-11)
- HTRF® Ligand Binding Assay for the Chemokine Receptor CXCR4 (08-Sep-10)
- Live-Cell Assay to Interrogate GPCRs by Monitoring cAMP Levels using a Bioluminescent Readout (08-Sep-10)
- Use of a Flexible Multipurpose Automated 1536-well Microplate Dispenser for HTS (08-Sep-10)
- Homogeneous Cell-based Signal Transduction Assays (21-Apr-10)
HTRF in Drug Discovery (2)
ISSX (7)
- A Simple, Robust Automated Multiplexed Cell-Based Assay Process for the Assessment of Mitochondrial Dysfunction and Cytotoxicity (23-Sep-11)
- Automated 384-Well Cell-Based Cytochrome P450 Inhibition Assays using Cryopreserved Human Hepatocytes in Suspension (02-Feb-11)
- Automated Triplexed Hepatocyte-Based Viability and CYP1A and CYP3A Induction Assays in 96- and 384-well Microplates (10-Sep-10)
- Combining Luminescence-based CYP Inhibition Assays and Simple, Robust Instrumentation for Use in Automated Cytochrome P450 Profiling (10-Sep-10)
- Utility of Automated Drug Transport Assays in 96-Well Format, using Permeable Support Systems (10-Sep-10)
- Automation of a Luminescent Assay to measure UDP-glucuronosyltransferase (UGT) Enzyme Activity (11-Sep-09)
- Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds (13-Aug-09)
International Poultry Expo (1)
LabAutomation (34)
- Automated Compound Profiling Applications for the Assessment of Lead Compound Off-target Effects (01-Jul-11)
- Efficacy of Using a Combination Microplate Washer for Vacuum-Based DNA Sequencing Reaction Cleanup (01-Jul-11)
- A Fluorescence Microplate-Based Assay Workflow for High-Throughput Screening of Compounds Modulating Autophagy in Living Cells (02-Feb-11)
- A Homogeneous Assay to Quantify Endogenous AKT Phosphorylation in Human Umbilical Endothelial Cells (02-Feb-11)
- Automated 384-Well Cell-Based Cytochrome P450 Inhibition Assays using Cryopreserved Human Hepatocytes in Suspension (02-Feb-11)
- Automated Triplexed Hepatocyte-Based Viability and CYP1A and CYP3A Induction Assays in 96- and 384-well Microplates (02-Feb-11)
- Automated Washing of Multiplex Bead Based Assays for the MAGPIX® Reader System (02-Feb-11)
- Live-Cell Assay to Interrogate GPCRs by Monitoring cAMP Levels using a Bioluminescent Readout (02-Feb-11)
- Utility of Automated Drug Transport Assays in 96-Well Format, using Permeable Support Systems (02-Feb-11)
- Automated Triplexed Hepatocyte-Based Viability and CYP1A and CYP3A Induction Assays in 96- and 384-well Microplates (10-Sep-10)
- A Novel Homogeneous, Fluorescence-based Technology for Dual Measure of Phosphodiesterases and Their Downstream Effector Kinase Activities in Biochemical and Cell-based Assays (26-Jan-10)
- Automated Cell Dispensing into 1536-Well Microplates for HTS Screening (26-Jan-10)
- Automated Cytotoxicity Profiling Using the EL406 Washer Dispenser with CELLestial™ Assay Kits for Microplates (26-Jan-10)
- Automated Processing of a Homogeneous phospho-ERK1/2 Assay for Use as a Generic GPCR Sensor (26-Jan-10)
- Automated Washing of Magnetic Bead xMAP Assays for Multiplexed mRNA and Metabolic Hormone Assays (26-Jan-10)
- Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds (26-Jan-10)
- Utility of Hybrid Multi-Mode Readers using Both Monochromator- and Filter-Based Detection Capabilities as Demonstrated with FP, TR-FRET, and Fluorescence Intensity Assays for the Measurement of ADP Accumulation (26-Jan-10)
- Versatile, Cost-effective Automation of Avian Influenza and Mycoplasma Gallisepticum-Synoviae ELISAs (26-Jan-10)
- Automation of a Microplate Cell-based Assay to Measure Activity of the Histamine H1 G-protein-coupled Receptor Using A Novel 3-D Cell Culture Technique (22-Jan-10)
- Automated ELISA Liquid Handling with EL406 Combination Microplate Washer Dispenser (02-Feb-09)
- Automated Triplex Assay to Assess Cell Viability, Cytotoxicity and Apoptosis (02-Feb-09)
- Invitrogen's Predictor™ hERG Fluorescence Polarization Assay Using BioTek's Synergy™ 4 Multi-Mode Microplate Reader with Hybrid Technology™ (02-Feb-09)
- Novel Gyrasol Sensor Assay Platform with the Hybrid Technology™ Multi-Mode Reader Synergy™ 4 (02-Feb-09)
- Optimizing Robustness of the Membrane-free, Oris™ Cell Migration Assay for High Throughput Screening using the BioTek Synergy™ HT Multi-Mode Microplate Reader (02-Feb-09)
- Volume Scaling of the Transcreener® ADP2 FP Assay on the BioTek Synergy™ 2 and 4 Multi-Mode Microplate Readers Allows For Easy Transition From Assay Development to High-Throughput Screening (02-Feb-09)
- Validation of a Suite of Invitrogen Assay Technologies on BioTek Instruments (21-Feb-08)
- Fluorescence Intensity, FRET, and TR-FRET Homogeneous Assay Technologies from Invitrogen™ Validated on BioTek’s new Versatile Hybrid Microplate Reader, Synergy™ 4 (23-Jan-08)
- Synergy™ 2 Multi-Mode Microplate Reader: A Novel Approach to Detection for HTS and Drug Discovery (19-Sep-06)
- Using BioTek’s ELx405™ Select CW Microplate Washer to Wash Loosely Adherent Tissue Culture Cells (29-Dec-04)
- MicroFill: A 96-/384-Well Microplate Reagent Dispenser for HTS and Drug Discovery (06-Apr-04)
- Applications of an Automated Microplate Stacking Device for HTS and Multi-Instrument Interface (26-Feb-04)
- The ELx405 384-Well Microplate Washer: Designed to Meet the Rigors of Biomolecular Screening (19-Feb-04)
- Synergy HT: A Unique Multi-Detection Microplate Reader for HTS and Drug Discovery (20-Feb-03)
- Using BioTek’s Precision 2000 Automated Pipetting System for Microarray Sample Preparation (01-Jan-00)
Laboratory Robotics Interest Group (6)
- Automation of a Luminescent Assay to measure UDP-glucuronosyltransferase (UGT) Enzyme Activity (11-Sep-09)
- Low Volume Nucleic Acid Quantification using A Multi-Volume Microplate Spectrophotometer System (11-Sep-09)
- A Simple and Robust Automated Kinase Profiling Platform using Luminescent ADP Accumulation Technology (13-Aug-09)
- Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds (13-Aug-09)
- Automation of Luminescence-based CYP Inhibition Assays using BioTek Instrumentation for use in Drug Discovery (29-Apr-09)
- Synergy™ HT: A Multi-Mode Microplate Reader for Today's High Performance Luminescence Research (14-Jun-05)
MipTec (22)
- An Automated, High Throughput Method for the Quantification of Endogenous Cellular Kinase Activity (28-Sep-12)
- Analysis of a New High Throughput Screening Detection Technology for Rapid hERG Safety Testing using a Fluorescence Polarization Assay (28-Sep-12)
- Automation of a Homogeneous Proximity Assay for Immunogenicity Testing of Biological Drug Products (28-Sep-12)
- Determination of Endogenous Cellular Kinase Activity through the Use of an Automated, High Throughput AlphaScreen®-Based Method (28-Sep-12)
- Rapid Screening of a Cell-based Assay for GLP-1 Receptor Using a Natural Product Library (28-Sep-12)
- Screening for Inhibitors of BRD4 Bromodomain 1 using a Homogeneous Proximity Assay (28-Sep-12)
- A Simple, Robust Automated Multiplexed Cell-Based Assay Process for the Assessment of Mitochondrial Dysfunction and Cytotoxicity (23-Sep-11)
- Analytical Performance of a Higher Throughput Multi-Volume Microplate Accessory for Microplate Spectrophotometer Platforms (23-Sep-11)
- Automation of a Novel Cell-Based ELISA for Cell Signaling Pathway Analysis (23-Sep-11)
- Ruggedness Testing Including an Evaluation of Automation of a Cell- Based Bioluminescent TNFα Blocker Bioassay (23-Sep-11)
- Automation of a Generic Fluorescence Methyltransferase Activity Assay (15-Sep-11)
- Automated Compound Profiling Applications for the Assessment of Lead Compound Off-target Effects (01-Jul-11)
- Homogeneous Cell-Based Signal Transduction Assays using a Novel 3-D Cell Culture Matrix (05-Oct-10)
- HTRF® Ligand Binding Assay for the Chemokine Receptor CXCR4 (08-Sep-10)
- Live-Cell Assay to Interrogate GPCRs by Monitoring cAMP Levels using a Bioluminescent Readout (08-Sep-10)
- Use of a Flexible Multipurpose Automated 1536-well Microplate Dispenser for HTS (08-Sep-10)
- A Cost-Effective Workflow for High-Throughput Screening of G Protein-Coupled Receptors (GPCR) (28-Oct-09)
- Automation of a Luminescent Assay to measure UDP-glucuronosyltransferase (UGT) Enzyme Activity (11-Sep-09)
- A Simple and Robust Automated Kinase Profiling Platform using Luminescent ADP Accumulation Technology (13-Aug-09)
- Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds (13-Aug-09)
- Automation of Luminescence-based CYP Inhibition Assays using BioTek Instrumentation for use in Drug Discovery (29-Apr-09)
- Automating a Lowry Protein Assay with BioTek's Precision™ XS Microplate Sample Processor (02-Jun-04)
PEGS (2)
Pittcon (1)
Planet xMAP (6)
- Critical Washer Parameters for Washing Beads (12-Oct-12)
- Automated Washing of Cancer Biomarker Assays (30-Sep-11)
- Differential Cancer Biomarker Secretion of Cultured Human Cells (30-Sep-11)
- Automated Processing of Bead-based Cytokine Multiplex Assays using Multiple Washer Platforms (19-Oct-10)
- Critical Automated Washer Parameters for Optimal Washing and Bead Recovery of MagPlex and MicroPlex Microspheres (13-May-10)
- Automated Washing of Magnetic Bead xMAP Assays for Multiplexed mRNA and Metabolic Hormone Assays (13-Oct-09)
SLAS (19)
- An Automated Profiling Application using a Direct, Cell-Based, Target-Compound Interaction Assay for G9a Histone Methyltransferase and Bromodomain Proteins (14-Jan-13)
- An Automated, High Throughput Method for the Quantification of Endogenous Cellular Kinase Activity (14-Jan-13)
- Analysis of a New High Throughput Screening Detection Technology for Rapid hERG Safety Testing using a Fluorescence Polarization Assay (14-Jan-13)
- Assessment of New Developments in ADCC Assays (14-Jan-13)
- Automated, High Throughput, HTRF®-Based Detection of Histone Methyltransferase and Demethylase Enzyme Activity (14-Jan-13)
- Automation of a Homogeneous Proximity Assay for Immunogenicity Testing of Biological Drug Products (14-Jan-13)
- Determination of Endogenous Cellular Kinase Activity through the Use of an Automated, High Throughput AlphaScreen®-Based Method (14-Jan-13)
- Live-Cell Biosensor Assay Used To Interrogate GPCRs: Comparative Analysis of Biosensor Variants (14-Jan-13)
- Rapid Screening of a Cell-based Assay for GLP-1 Receptor Using a Natural Product Library (14-Jan-13)
- Screening for Inhibitors of BRD4 Bromodomain 1 using a Homogeneous Proximity Assay (14-Jan-13)
- A Simple, Robust Automated Multiplexed Cell-Based Assay Process for the Assessment of Mitochondrial Dysfunction and Cytotoxicity (08-Feb-12)
- An Automated, Cell-based Platform for the Rapid Detection of Novel Androgen Receptor Modulators (08-Feb-12)
- Automated Solutions for Cellular Screening and Characterization of Therapeutic Antibodies for Antibody-Dependent Cellular Cytotoxicity Utility (08-Feb-12)
- Automation of a Generic Fluorescence Methyltransferase Activity Assay (08-Feb-12)
- Automation of a Novel Cell-Based ELISA for Cell Signaling Pathway Analysis (08-Feb-12)
- Efficacy of Using a Combination Microplate Washer for Vacuum-Based DNA Sequencing Reaction Cleanup (08-Feb-12)
- Improving Cell-Mediated Cytotoxicity Assessment through the Use of an Automated Luminescent ADCC Assay (08-Feb-12)
- Modular Bench Top Automation (08-Feb-12)
- Screening for Optimal Algal Cell Growth and Neutral Lipid Production Conditions in Microplates (08-Feb-12)
Society Of Toxicology (1)
Society for Biomolecular Sciences (27)
- A Fluorescence Microplate-Based Assay Workflow Enabling the Functional Characterization of Multi-Drug Resistance Transporters in Living Cells (31-Mar-11)
- Utility of a Sensitive, Fluorescence-Based Assay for the Detection of Histone Deacetylase 6 (HDAC6) Activity (31-Mar-11)
- Utility of The Synergy™ H1 Multi-Mode Microplate Reader in Combination with Transcreener® ADP2 FP, TR-FRET and FI Assays for The Measurement of ADP Accumulation (31-Mar-11)
- A Homogeneous Assay to Quantify Endogenous AKT Phosphorylation in Human Umbilical Endothelial Cells (02-Feb-11)
- Automated 384-Well Cell-Based Cytochrome P450 Inhibition Assays using Cryopreserved Human Hepatocytes in Suspension (02-Feb-11)
- Automated Triplexed Hepatocyte-Based Viability and CYP1A and CYP3A Induction Assays in 96- and 384-well Microplates (02-Feb-11)
- Utility of Automated Drug Transport Assays in 96-Well Format, using Permeable Support Systems (02-Feb-11)
- Automation of Cell-Based Assays (10-Dec-10)
- Development of a Live-Cell Based Reactive Oxygen Species (ROS) Assay for use in High-Content Screening of Drug Candidates Using The BioTek Synergy Mx Microplate Reader (21-Apr-10)
- Homogeneous Cell-based Signal Transduction Assays (21-Apr-10)
- Novel Fluorescence-Based Microplate Assay for Screening Inhibitors of Thioredoxin and Protein Disulfi de Isomerase (21-Apr-10)
- Quencher Dyes Can Alter the Pharmacokinetic Response Profiles of Living Cells in Fluorescence-based Calcium Mobilization Assays (21-Apr-10)
- Cytotoxicity Profiling of The Anticancer Agent Thiostrepton (09-Mar-10)
- Automation of a Microplate Cell-based Assay to Measure Activity of the Histamine H1 G-protein-coupled Receptor Using A Novel 3-D Cell Culture Technique (22-Jan-10)
- BacMam-Enabled Cellular Assays Measuring Histone Posttranslational Modifications (05-May-09)
- Automated ApoTox-Glo Assay to Simultaneously Assess Cell Viability, Cytotoxicity and Apoptosis (29-Apr-09)
- Automated ELISA Liquid Handling with EL406 Combination Microplate Washer Dispenser (29-Apr-09)
- Automation of Luminescence-based CYP Inhibition Assays using BioTek Instrumentation for use in Drug Discovery (29-Apr-09)
- Automation of Predictor™ hERG Fluorescence Polarization Assay using Precision™ Automated Pipetting System for Serial Dilution of Small Molecule Drugs for IC50 Determinations (29-Apr-09)
- Multiplexed GPCR Assays using HTRF® Technology (29-Apr-09)
- Optimization and Validation of a high-throughput homogeneous Time-Resolved Fluorescence (HTRF®) assay for inhibitors to Class IA Phosphoinositide 3-kinase isoform activity (29-Apr-09)
- The Synergy Family of Readers; A Lower Cost High Performance Alternative for Running AlphaScreen Assays (09-Apr-08)
- Using Synergy™ 2 Multi-Mode Microplate Reader to run cAMP and Tumor Necrosis Factor HTRF® assays for High-Throughput Screening (23-Apr-07)
- Synergy™ 2 Multi-Mode Microplate Reader: A Novel Approach to Detection for HTS and Drug Discovery (19-Sep-06)
- The ELx405™ Microplate Washer: A Family of Washers to Meet the Diverse Needs of Biological Screening (08-Sep-05)
- Performance Verification of BioTek's Precision 2000 Using Artel's Multichannel Volume Verification (MVV) System (29-Oct-03)
- A Flexible, Multi-Purpose, Multi-Detector HTS Automated Platform (01-Jan-00)







