Applications - Presentations
Cellular Energy Flux in Real-Time: High-Throughput Metabolism & Mitochondrial Function Assays
11-Dec-15Related Products: BioSpa 8, Cytation Multi-Mode, MultiFlo FX, Synergy 2, Synergy H1, Synergy Neo2
Presenters: Wendy Goodrich, Applications Scientist, BioTek Instruments and Dr. James Hynes, Head of Research & Development, Luxcel Biosciences
Join us as we outline how a panel of microplate-compatible fluorescence-based assays developed by Luxcel Biosciences can be used to examine cell metabolism. These assays interrogate oxidative phosphorylation (MitoXpress-Xtra), glycolytic flux (pH-Xtra), and cellular oxygenation (MitoXpress-Intra) facilitating, convenient, high-throughput metabolic assessments. We will describe how, using this technology, drug toxicity can be screened, and using the Warburg effect as an example, how perturbed cell metabolism can be interrogated. We will also describe how levels of cellular oxygenation can now be conveniently measured, offering opportunities for new insights into hypoxia and related signaling.