405 Touch Washer

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High resolution, advanced touch screen User Interface

High resolution, advanced touch screen User Interface

USB flash drive ports for convenient file transfer and storage

USB flash drive ports for convenient file transfer and storage

Optimized for loosely adherent monolayers: low flow rates, angled dispensing

Optimized for loosely adherent monolayers: low flow rates, angled dispensing

Patented Verify™ clog detection technology and Ultrasonic Advantage™

Patented Verify™ clog detection technology and Ultrasonic Advantage™

The 405 Touch Microplate Washer features the new patented* Verify™ technology, which runs an automated QC check for manifold tube blockage, and visually reports any failed wells.  The patented Ultrasonic Advantage™ can then be used to automatically and thoroughly clean the aspirate and dispense manifolds. The 405 Touch, with the unique Verify and Ultrasonic Advantage features, overcomes the common problem of undetected washer manifold clogging which can lead to assay failure. The 405 Touch is the first self-checking, self-maintaining microplate washer available!

The 405™ Touch Microplate Washer incorporates a high resolution touch screen user interface for intuitive and flexible programming of 96- and 384-well microplate wash protocols. The extensive onboard software seamlessly guides users through protocol development, instrument maintenance and operation. For those who prefer computer control or require 21 CFR Part 11 compliance, the 405 Touch can be controlled with optional LHC™ Software.

Cell-based assays and microsphere-based assays are easily run with the 405 Touch’s unique set of available features and modules for gentle washing vacuum filtration and biomagnetic separation. The 405 Touch is Luminex® xMAP® approved; a range of configurations is available for this and a broad variety of other microplate washing applications. Review the models and specifications sections for details on all the possible configurations, there’s certain to be one that fits your laboratory’s requirements.

With its color graphical user interface, fail-safe QC and maintenance tools, and compact, robot-compatible design, the 405 Touch is an easy to use microplate washing solution for a wide range of applications.

* EP 1 637 887


US Federal Government customers: This product is available on GSA contract. Contact BioTek Customer Care with questions or submit a Quote Request Form to receive pricing and information on specific models (please note GSA Contract in the Comments field).

xMAP® is a registered trademark of Luminex® Corporation.
FLIPR® is a registered trademark of Molecular Devices®

 

Hardware features and options:

  • Patented built-in Verify sensor automatically checks dispense / aspirate performance and reports clogged locations in the color graphical display.

Washer-Verifier

  • Accommodates 96- and 384-well microplates
  • High resolution touch screen user interface
  • Onboard computer running Microsoft® Windows® CE
  • Patented built-in Ultrasonic Advantage automatically cleans clogged tubes
  • Two USB flash drive ports enable convenient file transfer, storage and operation
  • Automated internal 4-buffer switching
  • Internal positive displacement pump eliminates use of troublesome pressure delivery systems and allows use of any size dispense reservoir
  • Built-in priming trough allows automatic manifold priming and rinsing during both operation and maintenance modes and eliminates need for blank plates when used in automated robotic systems
  • All washers vacuum filtration ready (accessory filtration modules sold separately)
  • All washers biomagnetic separation ready (accessory magnets sold separately)

405 Select TS

  • 96-/384-well washing with patented 96-tube Dual-Action™ manifold
  • Cell washing is optimized with two low-flow rates and 20° angled dispense tubes ideal for washing loosely adherent cell monolayers

dual-action-manifold

405 HT TS

  • Fast 384-well washing with patented 192-tube Dual-Action™ manifold for independent dispense and aspiration control for precise overfill washing and overflow protection:
  • Superior tube-in-tube aspiration manifold design for 384-well washing with buffers not containing surfactant
  • 96-well washing ready with optional 96-tube Dual-Action manifold

405 TS

  • 405 TS models automate basic 96-well dispensing and aspiration

Software Features:

  • Context sensitive help system complete with recommendations, diagrams and images is only a key press away when questions arise
  • Pre-defined protocols and instructional videos walk users through instrument setup and basic use
  • Fully customizable protocol parameters for individualized wash requirements - gentle cell-washing to vigorous wash for high-binding assays
  • AutoPrime
  • Additional software flexibility and 21 CFR Part 11 compliance with Liquid Handling Control™ (LHC) Software for method development, downloading and washing plates.
  • Run protocols created onboard, downloaded from LHC™ Software or transferred on USB drive
Part #
384-well
96-well
Optimized Cell Washing
4-Buffer Switching
Biomagnetic Separation**
Vacuum Filtration**
405TSHT
 *
   
 
405TSHTV
 *
 
 
405TSU
     
405TSUV
 •
 
 
405TSUS
 
 
405TSUSQ
 •
 
405TSUVS
 
405TSUVSQ
 •
405TSR
 
 
 
   
405TSRV
 
 
   
405TSRS
 
 
 
 
405TSRSQ
 
   
405TSRVS
 
 
 
405TSRVSQ
 
 

* 96-well washing available with optional manifold PN 1170010, sold separately
** With available accessory module sold separately

 

405™ Touch Microplate Washer Configurations
  Feature Design
HT Faster 384-well microplate washing
V Automated Internal 4-Buffer Switching  
S Ultrasonic Advantage™
  • Built-in ultrasonic cleaner for manifold self-maintenance
U 96-/384-well microplate washing
  • 96-tube (8 x 12) manifold
  • Dual-Action™
R 96-well microplate washing
  • 96-tube (8 x 12) manifold
Q Verify™ technology
  • Built-in clog detection for dispense and aspirate tubes

 

 

General
Microplate Types 96- and 384-well
Low profile and standard height
Solid and filter bottom (option)
Filter pore sizes from 0.45 µm to 1.2 µm
Onboard Software Create, edit or run multiple protocols
Software (pc control) LHC2 pc software
LHC2 Secure for 21 CFR Part 11 compliance (option)
SiLA Compliant driver (option)
Separation Biomagnetic separation, vacuum filtration (optional)
Shaking Programmable up to 60 minutes
Slow, medium, fast or variable
Soaking Programmable up to 60 minutes
Ultrasonic Advantage™ Yes (option)
Verify™ clog detection Yes (option)
Automation BioStack and 3rd party automation compatible
BioSpa 8 Automated Incubator compatible
Washing
Manifold Types 96-well washing: 96-tube manifold - straight dispense tubes
96- and 384-well washing: 96-tube Dual-Action manifold - 20° angled dispense tubes
384-well washing (fast): 192-tube Dual-Action manifold - 7° angled dispense tubes
Volume Range 25 - 3,000 µL/well, in 1 µL increments
Wash Cycles 1 - 250
Buffer/reagent selection Auto switching (internal) for up to 4 buffers (option)
Supply Bottle 4 L or 10 L (optional)
Dispense Precision <3% CV: 300 µL/well (96-well washing)
<4% CV: 80 µL/well (384-well washing)
Residual Volume < 2 µL/well (96- & 384-well plates)
96-tube manifold for 96 wells; 192-tube for 384 wells
Wash Speed 96-wells, 300 µL/well, 3 cycles; <30 seconds
384-wells,100 µL/well, 3 cycles: <80 seconds
384-wells, 400 µL/well, 1 cycle: <20 seconds
Flow Rates High flow to low flow
Optimized rates for cell assays
Sterilization Chemical
Vacuum Filtration Selectable: Approximate final at 30 seconds:
Lowest: -38 mmHg
Low: -113 mmHg
Medium: -200 mmHg
High: -390 mmHg
Highest: -506 mmHg

Vacuum filtration time range: 5 to 999 seconds
Physical Characteristics
Power 100 - 240 Volts AC. 50/60 Hz
Dimensions 14" W x 17" D x 10" H
(35.6 x 43.2 x 25.4 cm)
Weight With internal buffer switching - 36 lbs (16.5 kg)
Without - 30 lbs (13.5 kg)
Regulatory
Regulatory CE and TUV marked. ROHS compliant. In Vitro Diagnostic use models are available.

Specifications are subject to change. Performance values represent the average observed factory test values.

Optional

BioSpa 8 Automated Incubator

BioSpa 8 Automated Incubator

BioSpa 8 is an automated incubator linking BioTek readers or imagers together with washers and dispensers for full workflow automation of up to 8 microplates. Temperature, CO2/O2 and humidity levels are controlled and monitored through the BioSpa software to maintain an ideal environment for cell cultures during all experimental stages.


BioStack Microplate Stacker

BioStack Microplate Stacker

BioStack™ is a compact and versatile microplate stacker compatible with BioTek’s washers, dispensers, detectors and imaging systems. BioStack offers rapid plate exchange speeds to increase throughput and enhance productivity, accommodating assay workflows both with and without plate lids.


Liquid Handling Control™ Software

Liquid Handling Control™ Software

Software is a powerful yet flexible interface for use with BioTek’s liquid handlers including the 405™ Microplate Washer, the ELx405™ Select Deep Well Washer, the EL406™ Washer Dispenser and the MultiFlo™ Dispenser. New LHC Secure offers compliance to the FDA directive 21 CFR Part 11 or whenever additional security is required.


Standard (Included)

Operators Manual

MANUAL Operator's manuals can be obtained via the Customer Resource Center

Optional

BioStack Integration Kits

7310040 BioStack Integration Kit for 405™ TS and 405™ LS

Bottles & Tubing

1170031 4L dispense bottle with filter accessory has picture
1173000 Dispense Bottle - with Filter, 10L accessory has picture
1173002 Cap for Dispense Bottle - with Filter, 10L
1173003 Cap for Dispense Bottle - with Filter, 4L accessory has picture
7100531 Cap for Waste Bottle, 4L (Also fits 10L or 20L) accessory has picture
7100533 Waste Tubing Set accessory has picture
7100534 Waste Bottle, 4L accessory has picture
7100537 Dispense Tubing Set – 4 Buffers
7100538 Dispense Tubing Set –1 Buffer accessory has picture
7100542 Waste Bottle with Level Sensing, 4L accessory has picture
7100543S Waste Set with Level Sensing, 4L Bottles accessory has picture
7100544 Cap for Waste Bottle with Level Sensing, 4L accessory has picture
7100556 Waste Bottle and Tubing, 20L accessory has picture
7100557 Waste Bottle and Tubing, 10L accessory has picture

Cables

75110 Serial cable, 9-pin male to 9-pin male

Dispense/Waste Systems

1170528S Complete Dispense System, 10L Bottles accessory has picture
1170529S Complete Dispense System, 4L Bottles accessory has picture
1170530 Complete Dispense/Waste System 115V/230V, 4L Bottles accessory has picture
1170531S Complete High Flow Waste System 115V/230V, 10L Bottles
1170532 Complete Dispense/High Flow Waste System 115V/230V, 4L Bottles accessory has picture
1170533 Complete Dispense/High Flow Waste System 115V/230V, 10L Bottles
1170534S Complete Waste System 115V/230V, 10L Bottles
1170535 Complete Dispense/Waste System 115V/230V, 10L Bottles
1170554 Complete Dispense/Waste System 115V/230V, 20 L Bottles
1170555S Complete Waste System 115V/230V, 20L bottles
1170556 Complete Dispense/High Flow Waste System 115V/230V, 20L Bottles
1170557S Complete High Flow Waste System 115V/230V, 20L Bottles
1170560 Complete Direct Drain Waste System 115V/230V, 4L Bottles
1170561 Direct Drain Waste System Upgrade Kit 115V/230V, 4L Bottles
1170562 Complete Direct Drain High Flow Waste System 115V/230V, 4L Bottles
7100582S Vacuum Set with Level Sense Assembly, 10L accessory has picture
7100746S Complete Waste System 115V/230V, 4L Bottles accessory has picture
7100753S Complete High Flow Waste System 115V/230V, 4L Bottles
7100754 High Flow Vacuum Pump 115/230V
7103034 Standard Vacuum Pump 115V/230V accessory has picture

Filters

01310 Filter for Dispense Bottle
48294 Filter for Waste Tubing accessory has picture

Manifolds

1170010 96-Tube Dual-Action Manifold Kit, with 7° dispense tubes and tube-in-tube aspiration manifold kit for 405 HT TS and 405 HT LS models only
1172046S 96-tube Dual-Action™ Tube-in-Tube Aspiration Manifold accessory has picture
7102068S 96-tube Dual-Action™ 7° Dispense Manifold

Miscellaneous

01113 Silencing Muffler for Standard Vacuum Pump
1170008 96-well Vacuum Filtration Kit accessory has picture
1170009 96-/384-well Vacuum Filtration Kit accessory has picture
1170013 15' extension kit for use with robotic system integrations of 405 TS / LS
4030551 Vacuum Gauge/Regulator
7100025S Stylus Kit for any 405™/ELx405™ Select Deep Well manifold accessory has picture
7102215 384-well Ring Magnet accessory has picture
7102216 96-well Ring Magnet accessory has picture
7103016 96-well Flat Magnet accessory has picture
7103017 384-well Flat Magnet accessory has picture
7210515 3-Instrument Rack – for third party robotic system integration accessory has picture

Product Qualification Packages

1170522 405 TS Qualification Package - IQ/OQ/PQ

Test Plates & Reagents

1240001 Replacement 405 Verify test plate kit accessory has picture

Waste Systems

1170555S Complete Waste System 115V/230V, 20L Bottles
7100764S Waste set with Level Sensing, 20L Bottles

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