405 Touch Microplate Washer
The 405 Touch Microplate Washer features the new patented* Verify™ Technology, which runs an automated QC check for manifold tube blockage, and visually reports any failed wells. The patent pending Ultrasonic Advantage™ can then be used to automatically and thoroughly clean the aspirate and dispense manifolds. The 405 Touch, with the unique Verify and Ultrasonic Advantage features, overcomes the common problem of undetected washer manifold clogging which can lead to assay failure. The 405 Touch is the first self-checking, self-maintaining microplate washer available!
The 405™ Touch Microplate Washer incorporates a high resolution touch screen user interface for intuitive and flexible programming of 96- and 384-well microplate wash protocols. The extensive onboard software seamlessly guides users through protocol development, instrument maintenance and operation. For those who prefer computer control or require 21 CFR Part 11 compliance, the 405 Touch can be controlled with optional LHC™ Software.
Cell-based assays and microsphere-based assays are easily run with the 405 Touch’s unique set of available features and modules for gentle washing vacuum filtration and biomagnetic separation. The 405 Touch is Luminex® xMAP® approved; a range of configurations is available for this and a broad variety of other microplate washing applications. Review the models and specifications sections for details on all the possible configurations, there’s certain to be one that fits your laboratory’s requirements.
With its color graphical user interface, fail-safe QC and maintenance tools, and compact, robot-compatible design, the 405 Touch is an easy to use microplate washing solution for a wide range of applications.
* EP 1 637 887
US Federal Government customers: This product is available on GSA contract. Contact BioTek Customer Care with questions or submit a Quote Request Form to receive pricing and information on specific models (please note 'GSA Contract' in the Comments field).
xMAP® is a registered trademark of Luminex® Corporation.
FLIPR® is a registered trademark of Molecular Devices®
Hardware features and options:
- Patented built-in Verify sensor automatically checks dispense / aspirate performance and reports clogged locations in the color graphical display.
- Accommodates 96- and 384-well microplates
- High resolution touch screen user interface
- Onboard computer running Microsoft® Windows® CE
- Patent pending built-in Ultrasonic Advantage automatically cleans clogged tubes
- Two USB flash drive ports enable convenient file transfer, storage and operation
- Automated internal 4-buffer switching
- Internal positive displacement pump eliminates use of troublesome pressure delivery systems and allows use of any size dispense reservoir
- Built-in priming trough allows automatic manifold priming and rinsing during both operation and maintenance modes and eliminates need for blank plates when used in automated robotic systems
- All washers vacuum filtration ready (accessory filtration modules sold separately)
- All washers biomagnetic separation ready (accessory magnets sold separately)
405 Select TS
- 96-/384-well washing with patented 96-tube Dual-Action™ manifold
- Cell washing is optimized with two low-flow rates and 20° angled dispense tubes ideal for washing loosely adherent cell monolayers

405 HT TS
- Fast 384-well washing with patented 192-tube Dual-Action™ manifold for independent dispense and aspiration control for precise overfill washing and overflow protection:
- Superior tube-in-tube aspiration manifold design for 384-well washing with buffers not containing surfactant
- 96-well washing ready with optional 96-tube Dual-Action manifold
405 TS
- 405 TS models automate basic 96-well dispensing and aspiration
Software Features:
- Context sensitive help system complete with recommendations, diagrams and images is only a key press away when questions arise
- Pre-defined protocols and instructional videos walk users through instrument setup and basic use
- Fully customizable protocol parameters for individualized wash requirements - gentle cell-washing to vigorous wash for high-binding assays
- AutoPrime
- Additional software flexibility and 21 CFR Part 11 compliance with Liquid Handling Control™ (LHC) Software for method development, downloading and washing plates.
- Run protocols created onboard, downloaded from LHC™ Software or transferred on USB drive
Part # |
96-/384-well |
384-well |
96-well |
Optimized Cell Washing |
4-Buffer Switching |
Ultrasonic Advantage |
Verify Technology |
Biomagnetic Separation* |
Vacuum Filtration* |
405TSHT |
• |
• |
• |
• |
|||||
405TSHTV |
• |
• |
• |
• |
• |
||||
405TSU |
• |
• |
• | • | |||||
405TSUV |
• |
• |
• |
• |
• |
||||
405TSUS |
• |
• |
• |
• |
• |
||||
405TSUSQ |
• |
• |
• |
• |
• |
• |
|||
405TSUVS |
• |
• |
• |
• |
• |
• |
|||
405TSUVSQ |
• |
• |
• |
• |
• |
• |
• |
||
405TSR |
• |
• | • | ||||||
405TSRV |
•
|
• |
• | • | |||||
405TSRS |
• |
• | • | • | |||||
405TSRSQ |
• |
• |
• |
• |
• |
||||
405TSRVS |
• |
• |
• | • | • | ||||
405TSRVSQ |
• |
• |
• |
• |
• |
• |
* With available accessory module sold separately
| 405™ Touch Microplate Washer Configurations |
||
| Feature | Design | |
| HT | Faster 384-well microplate washing |
|
| V | Automated Internal 4-Buffer Switching | |
| S | Ultrasonic Advantage™ |
|
| U | 96-/384-well microplate washing |
|
| R | 96-well microplate washing |
|
| Q | Verify™ Technology |
|
| General | |
| Assays | ELISA Cell-based assays (model dependent) Magnetic bead, polystyrene bead
Filtration-to-waste processes |
| Separation | Biomagnetic separation, vacuum filtration |
| Microplate Types | 96- and 384-well (model dependent) Low profile and standard height Solid and filter bottom
|
| Shaking | Programmable in minutes and seconds, up to 60 minutes Intensities - slow, medium, fast or variable |
| Soak Time | Programmable in minutes and seconds, up to 60 minutes |
| Magnet | High strength 96- and 384-well designs Choice of two designs, custom for BioTek microplate washers: Flat: - Flat-bottom well - beads pulled to band across well bottom - Round-bottom well - beads pulled to button at well bottom Ring: - beads pulled to 4-zone ring at well bottom |
| Safety/Convenience/Maintenance | Waste and vacuum sensing, fluid and flow detection Aerosol cover Adjustment utility for plate positioning Overflow protection Preprogrammed maintenance routines |
| Automation | BioStack™ Microplate Stacker - up to 50 ANSI/SBS standard height plates (optional)
|
| Onboard Software | High resolution backlit LED touch screen UI 5.7 inch graphical color display Intel Atom processor running Windows CE Predefined sample wash protocols - ELISA, cell wash, biomagnetic separation and vacuum filtration Quick Menu Create or edit multiple custom protocols Run protocols created onboard, downloaded from LHC™ Software or transferred on USB flash drive |
| Software | Liquid Handling Control™ (LHC™), for PC wash protocol programming and execution (optional) |
| Operating Temperature | 15° C to 30° C (59° F to 86° F) |
| Interface | For PC control and BioStack™ integration – 1 USB port, 1 9-pin RS232 port For file transfer – 2 USB Flash Memory ports |
| Humidity | 10% to 85%, non-condensing |
| Electrical | 100 – 240 Volts AC 50/60 Hz, < 8.0 A |
| Washing | |
| Manifold Types | 96-well washing: 96-tube (8 X 12) manifold 96-/384-well washing: Dual-Action™ 96-tube (8 X 12) manifold 384-well washing: Dual-Action™ 192-tube (16 x 12) manifold |
| Washing Speed | Solid bottom plates: 96-Well: 3 asp. / disp. cycles, 300 µL/well, 96-tube manifold, final aspirate: <30 seconds 384-Well: 3 asp. / disp. cycles, 100 µL/well, 96-tube manifold, final aspirate: <80 seconds 1 asp. / disp. cycle, 400 µL/well, 384 wells, 192-tube manifold, final aspirate: <20 seconds Filter bottom plates: Variable, based on wash parameters |
| Fluid Delivery | One internal positive displacement pump |
| Vacuum Filtration | Selectable vacuum levels (approximate finals at 30 seconds): Lowest: -38 mmHg Low: -113 mmHg Medium: -200 mmHg High: -390 mmHg Highest: -506 mmHg Vacuum filtration time range: 5 to 999 seconds |
| Volume Range | 25 to 3,000 µL/well Selectable in 1 µL increments |
| Buffer Selection | Internal automatic switching for up to 4 wash buffers (optional) |
| Flow Rates | 1 to 11 Includes low flow, cell wash rates (model dependent) |
| Wash Cycles | 1 to 250 |
| Dispense Precision |
|
| Residual Volume | Solid bottom plates:
optimized prior to testing
Filter bottom plates:
0.45 µm plate, filtration 30 seconds, low vacuum, blotted
µm plate, filtration 10 seconds, low vacuum, blotted |
| Sterilization | Chemical 0.5% sodium hypochlorite, 70% isopropyl alcohol or 70% ethanol solution |
| Ultrasonic Cleaning | Built-in ultrasonic bath for protein and salt crystal buildup Programmable in hours and minutes, up to 60 minutes (model dependent) |
| Clog Detection | Built-in Verify technology detects dispense and aspirate tubes for blockage (model dependent) |
| Supply Bottle Volume | 4 L or 10 L (optional) |
| Physical Characteristics | |
| Dimensions | Depth: 17" (43.2 cm) Width: 14" (35.6 cm) Height: 10" (25.4 cm) |
| Weight | With internal buffer switching - 36 lbs (16.5 kg) Without - 30 lbs (13.5 kg) |
| Regulatory | |
| Regulatory | CE and TUV marked. In Vitro Diagnostic use models are available. |
Specifications are subject to change.
Optional

BioStack3 Microplate Stacker

Liquid Handling Control Software
Standard (Included) | ||
Operators Manual | ||
| MANUAL | Operator's manuals can be obtained via the Customer Resource Center | |
Request a Quote ▶



